Sinusitis Overview & Treatments

Sinusitis affects 37 million people each year,making it one of the most common health problems in the U.S. It is more prevalent than heart disease and asthma and has a greater impact on one’s quality of life than chronic back pain or congestive heart failure.

Sinusitis is defined as an inflammation of the sinus lining, and is commonly caused by structural issues such as ostial blockage, bacterial infections, viral infections or a combination of these. For many patients, symptoms vary and may include nasal congestion, facial discomfort, nasal discharge, headache and fatigue. Sinusitis is considered acute when symptoms last 4 weeks or less and chronic when it lasts 12 weeks or longer.

Treatment Options
The most common treatments for sinusitis aim to reduce mucosal swelling and relieve obstructions within the sinus ostium and ostio-meatal region, and include:

  • Medical therapy with antibiotics
  • Topical nasal steroid spray
  • However, at least 20 percent of patients do not respond adequately to medications.

For patients who have failed medical therapy, Endoscopic Sinus Surgery (ESS) is often the next step toward finding relief. During ESS, surgical instruments are used to remove small amounts of bone, tissue or growth blocking the sinus openings. Often, this removal of bone and tissue can require uncomfortable nasal packing after surgery and lead to post-surgery pain and scarring.

A Significant Unmet Clinical Need
Each year approximately 900,000 patients are left living with their sinus condition.These patients may not find adequate relief from medical therapy and are candidates for surgery, but for a variety of clinical or personal reasons choose not to undergo ESS using existing surgical instruments.